Wellbutrin SR Sustained-Release Tablets

Pronunciation: bue-PROE-pee-on
Generic Name: Bupropion
Brand Name: Wellbutrin SR

Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using Wellbutrin SR Sustained-Release Tablets outweigh the risks.

Wellbutrin SR Sustained-Release Tablets contains the same ingredient that is in Zyban, a medicine used to help certain patients stop smoking. Some patients using bupropion to help them stop smoking have also developed depression and certain other mental or mood problems, including suicidal thoughts or actions.

Family and caregivers must closely watch patients who take Wellbutrin SR Sustained-Release Tablets. It is important to keep in close contact with the patient's doctor. Contact the doctor at once if new, worsened, or sudden symptoms such as agitation, hostility, depressed mood, or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur. Discuss any questions with the patient's doctor.

Wellbutrin SR Sustained-Release Tablets are used for:

Treating depression. It may also be used for other conditions as determined by your doctor.

Wellbutrin SR Sustained-Release Tablets are an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.

Do NOT use Wellbutrin SR Sustained-Release Tablets if:

• you are allergic to any ingredient in Wellbutrin SR Sustained-Release Tablets


• you are taking any other medicine that contains bupropion


• you have a history of an eating disorder (eg, anorexia, bulimia) or seizures (eg, epilepsy)


• you are suddenly stopping the use of alcohol or sedatives (eg, benzodiazepines) after long-term use


• you are taking or have taken linezolid, methylene blue, or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Before using Wellbutrin SR Sustained-Release Tablets:

Some medical conditions may interact with Wellbutrin SR Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse


• if you have diabetes, kidney problems, liver problems (eg, cirrhosis), high blood pressure, heart problems (eg, congestive heart failure), or a recent heart attack


• if you have a history of seizures, a head injury, or a tumor in the brain or spinal cord


• if you are taking nonprescription weight loss medicines or stimulants

Some MEDICINES MAY INTERACT with Wellbutrin SR Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Amantadine, other antidepressants (eg, amitriptyline, fluvoxamine), antipsychotics (eg, haloperidol, risperidone), clopidogrel, corticosteroids (eg, prednisone), cyclophosphamide, HIV protease inhibitors (eg, nelfinavir), insulin, levodopa, linezolid, MAOIs (eg, phenelzine), methylene blue, nicotine patches, oral hypoglycemics (eg, glipizide), orphenadrine, sympathomimetics (eg, pseudoephedrine), theophylline, thiotepa, tiagabine, or ticlopidine because they may increase the risk of Wellbutrin SR Sustained-Release Tablets's side effects


• Carbamazepine, efavirenz, phenobarbital, phenytoin, rifampin, or ritonavir because they may decrease Wellbutrin SR Sustained-Release Tablets's effectiveness


• Antiarrhythmics (eg, flecainide, propafenone), beta-blockers (eg, metoprolol), phenothiazines (eg, thioridazine), selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), or tricyclic antidepressants (eg, nortriptyline) because the risk of their side effects may be increased by Wellbutrin SR Sustained-Release Tablets


• Tamoxifen because its effectiveness may be decreased by Wellbutrin SR Sustained-Release Tablets, which may lead to an increased risk of breast cancer recurrence in women with a history of breast cancer

This may not be a complete list of all interactions that may occur. Ask your health care provider if Wellbutrin SR Sustained-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Wellbutrin SR Sustained-Release Tablets:

Use Wellbutrin SR Sustained-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Wellbutrin SR Sustained-Release Tablets comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Wellbutrin SR Sustained-Release Tablets refilled.


• Take Wellbutrin SR Sustained-Release Tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Swallow Wellbutrin SR Sustained-Release Tablets whole. Do not break, crush, divide, or chew before swallowing.


• Several weeks may pass before your symptoms improve. Do not stop taking Wellbutrin SR Sustained-Release Tablets without checking with your doctor.


• Take your doses at the same times each day, at least 8 hours apart unless directed otherwise by your doctor. This may help to decrease the risk of seizures with Wellbutrin SR Sustained-Release Tablets.


• Continue to take Wellbutrin SR Sustained-Release Tablets even if you feel well. Do not miss any doses.


• If you miss a dose of Wellbutrin SR Sustained-Release Tablets, skip the missed dose and go back to your regular dosing schedule. Do not take more than 1 dose within 8 hours. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Wellbutrin SR Sustained-Release Tablets.

Important safety information:

• Wellbutrin SR Sustained-Release Tablets may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Wellbutrin SR Sustained-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Check with your doctor before you drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Wellbutrin SR Sustained-Release Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Wellbutrin SR Sustained-Release Tablets may increase your risk of seizures. Your risk may be greater if you also have certain medical conditions, use certain medicines, or if you use a lot of alcohol. Talk to your doctor to see if you may have a greater risk of seizures while taking Wellbutrin SR Sustained-Release Tablets.


• If you already drink alcohol or use sedatives, do not suddenly stop them without first checking with your doctor. Suddenly stopping them may increase your seizure risk.


• Do not take decongestants (eg, pseudoephedrine), stimulants, or diet pills while you are taking Wellbutrin SR Sustained-Release Tablets without first checking with your doctor. They may increase your risk of seizures.


• The risk of seizures may be greater if you take Wellbutrin SR Sustained-Release Tablets in high doses or for a long time. Do NOT take more than the recommended dose, change your dose, or use Wellbutrin SR Sustained-Release Tablets for longer than prescribed without checking with your doctor.


• Children, teenagers, and young adults who take Wellbutrin SR Sustained-Release Tablets may be at increased risk of suicidal thoughts or actions. Watch all patients who take Wellbutrin SR Sustained-Release Tablets closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.


• If you have trouble sleeping, you may be taking your dose too close to bedtime. Talk with your doctor about changing your dosing schedule.


• Wellbutrin SR Sustained-Release Tablets contains the same ingredients as Zyban, a medicine used to help stop smoking, and Aplenzin, another medication used to treat depression. Do not take Wellbutrin SR Sustained-Release Tablets if you are also taking Zyban or Aplenzin. Discuss any questions or concerns with your doctor.


• Wellbutrin SR Sustained-Release Tablets may interfere with certain lab tests, including urine screenings for amphetamines. Be sure your doctor and lab personnel know you are taking Wellbutrin SR Sustained-Release Tablets.


• Use Wellbutrin SR Sustained-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects.


• Wellbutrin SR Sustained-Release Tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Wellbutrin SR Sustained-Release Tablets while you are pregnant. Wellbutrin SR Sustained-Release Tablets are found in breast milk. Do not breast-feed while taking Wellbutrin SR Sustained-Release Tablets.

Possible side effects of Wellbutrin SR Sustained-Release Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth; flushing; headache; increased sweating; increased urination; loss of appetite; nausea; nervousness; restlessness; ringing in the ears; stomach pain; taste changes; trouble sleeping; vomiting; weakness; weight changes.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); chest pain; confusion; dark urine; delusions; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; hearing problems or ringing in the ears; menstrual changes; new or worsening mental or mood changes (eg, concentration problems, depression, panic attacks, aggressiveness, agitation, anxiety, impulsiveness, irritability, hostility, exaggerated feeling of well-being, inability to sit still); pale stools; red, swollen, blistered, or peeling skin; seizures; severe headache or dizziness; severe or persistent joint or muscle pain; severe or persistent nausea, vomiting, or stomach pain; severe or persistent nervousness, restlessness, or trouble sleeping; shortness of breath; suicidal thoughts or attempts; tremor; unusual swelling; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Wellbutrin SR side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fainting; fast, slow, or irregular heartbeat; fever; hallucinations; loss of consciousness; rigid or painful muscles; seizures; severe dizziness; slow or difficult breathing.

Proper storage of Wellbutrin SR Sustained-Release Tablets:

Store Wellbutrin SR Sustained-Release Tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tight, light-resistant container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Wellbutrin SR Sustained-Release Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Wellbutrin SR Sustained-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Wellbutrin SR Sustained-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Wellbutrin SR Sustained-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Wellbutrin SR resources

• Wellbutrin SR Side Effects (in more detail)
• Wellbutrin SR Use in Pregnancy & Breastfeeding
• Drug Images
• Wellbutrin SR Drug Interactions
• Wellbutrin SR Support Group
• 36 Reviews for Wellbutrin SR - Add your own review/rating

Compare Wellbutrin SR with other medications

• Depression

Walgreens Ibuprofen Junior Strength

Generic Name: ibuprofen

Dosage Form: tablet, chewable
Walgreen Co. Ibuprofen Tablets Drug Facts

Active ingredient (in each tablet)

Ibuprofen 100 mg (NSAID)*

*nonsteroidal anti-inflammatory drug

Purpose

Pain reliever/fever reducer

Uses

temporarily:

• reduces fever


• relieves minor aches and pains due to the common cold, flu, sore throat, headaches and toothaches

Warnings

Allergy alert: Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:

• hives


• facial swelling


• asthma (wheezing)


• shock


• skin reddening


• rash


• blisters

If an allergic reaction occurs, stop use and seek medical help right away.

Stomach bleeding warning: This product contains a nonsteroidal anti-inflammatory drug (NSAID), which may cause stomach bleeding. The chance is higher if the child:

• has had stomach ulcers or bleeding problems


• takes a blood thinning (anticoagulant) or steroid drug


• takes other drugs containing an NSAID [aspirin, ibuprofen, naproxen, or others]


• takes more or for a longer time than directed

Sore throat warning: Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult doctor promptly. Do not use more than 2 days or administer to children under 3 years of age unless directed by doctor.

Do not use

• if the child has ever had an allergic reaction to any other pain reliever/fever reducer


• right before or after heart surgery

Ask a doctor before use if the child has

• problems or serious side effects from taking pain relievers or fever reducers


• stomach problems that last or come back, such as heartburn, upset stomach, or stomach pain


• ulcers


• bleeding problems


• not been drinking fluids


• lost a lot of fluid due to vomiting or diarrhea


• high blood pressure


• heart or kidney disease


• taken a diuretic

Ask a doctor or pharmacist before use if the child is

• taking any other drug containing an NSAID (prescription or nonprescription)


• taking a blood thinning (anticoagulant) or steroid drug


• under a doctor’s care for any serious condition


• taking any other drug

When using this product

• mouth or throat burning may occur; give with food or water


• take with food or milk if stomach upset occurs


• long term continuous use may increase the risk of heart attack or stroke

Stop use and ask a doctor if

• the child feels faint, vomits blood, or has bloody or black stools. These are signs of stomach bleeding.


• stomach pain or upset gets worse or lasts


• the child does not get any relief within first day (24 hours) of treatment


• fever or pain gets worse or lasts more than 3 days


• redness or swelling is present in the painful area


• any new symptoms appear

Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away.

Directions

• this product does not contain directions or complete warnings for adult use


• do not give more than directed


• do not give longer than 10 days, unless directed by a doctor (see Warnings)


• find the right dose on chart below. If possible, use weight to dose; otherwise use age.


• if needed, repeat dose every 6-8 hours


• do not use more than 4 times a day

 

Dosing Chart
Weight (lb)	Age (yr)	Tablets
under 24	under 2	ask a doctor
24-35	2-3	1
36-47	4-5	1 ½
48-59	6-8	2
60-71	9-10	2 ½
72-95	11	3

Other information

• phenylketonurics: contains phenylalanine 6 mg per tablet


• do not use if printed foil under cap is broken or missing


• store at 20-25°C (68-77°F)


• see end panel for lot number and expiration date

Inactive ingredients

acesulfame K, aspartame, carnauba wax, croscarmellose sodium, D&C red no. 27, FD&C blue no. 1, flavors, hypromellose, magnasweet, magnesium stearate, mannitol, prosweet, silicon dioxide, sodium lauryl sulfate, soybean oil, succinic acid, whey protein concentrate

Questions or comments?

1-800-719-9260

Principal Display Panel

Compare to Motrin® Junior Strength active ingredient

Junior Strength

For Ages 2-11

Ibuprofen

Ibuprofen Tablets, 100 mg

Pain Reliever/Fever Reducer (NSAID)

Lasts up to 8 hours

See Expanded Dosing Directions

Grape Flavored

Tablets

Ibuprofen Tablets Carton

WALGREENS IBUPROFEN  JUNIOR STRENGTH ibuprofen  tablet, chewable

Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 0363-0521 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength IBUPROFEN (IBUPROFEN) IBUPROFEN 100 mg

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color PURPLE (Lavender) Score 2 pieces Shape ROUND Size 12mm Flavor GRAPE Imprint Code L521 Contains

Packaging # NDC Package Description Multilevel Packaging 1 0363-0521-62 1 BOTTLE In 1 CARTON contains a BOTTLE 1 24 TABLET In 1 BOTTLE This package is contained within the CARTON (0363-0521-62)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
ANDA	ANDA076359	05/05/2009

Labeler - Walgreen Company (008965063)

Revised: 05/2010Walgreen Company

More Walgreens Ibuprofen Junior Strength resources

• Walgreens Ibuprofen Junior Strength Side Effects (in more detail)
• Walgreens Ibuprofen Junior Strength Use in Pregnancy & Breastfeeding
• Drug Images
• Walgreens Ibuprofen Junior Strength Drug Interactions
• Walgreens Ibuprofen Junior Strength Support Group
• 51 Reviews for Walgreens Ibuprofen Junior Strength - Add your own review/rating

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• Aseptic Necrosis
• Back Pain
• Costochondritis
• Cystic Fibrosis
• Diffuse Idiopathic Skeletal Hyperostosis
• Dysautonomia
• Fever
• Frozen Shoulder
• Gout, Acute
• Headache
• Muscle Pain
• Osteoarthritis
• Pain
• Patent Ductus Arteriosus
• Period Pain
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WRM Clear

Generic Name: homeopathic veterinary de-wormer

Dosage Form: FOR ANIMAL USE ONLY
WRM Clear

Homeopathic remedy formulated for removal of Hook, Round and

Tapeworms.  For prevention by reducing susceptibility to infestations.

May also aid in recovery from worm effects and detoxify from effects of

conventional products.

100% natural, no chemicals added, no food withdrawal.

Dosage:

1-20lbs, 5 drops 3 times daily for 14 days to remove worms.

21-60lbs, 10 drops 3 times daily for 14 days to remove worms.

61-100lbs, 15 drops 3 times daily for 14 days to remove worms.

Over 100lbs, 20 drops 3 times daily for 14 days to remove worms.

Pets under 1lb, 2 drops in water, 3 times daily to remove worms.

Remedy may be dosed directly into mouth, in water or on food/treat.

Birds: Add 2 drops to at least 8oz of drinking water daily.

Prevention only: Use 3 times daily for 7 days, repeat every 60 days.

Remedy works by removing worms from pet's system.


Visit www.homeopetpro.com for detailed dosing and information.

Contact Veterinarian if problems persist.

Nat Mur, Nat Phos, Sulphur 6x, Arsenicum Alb, Nux Vom 8x, Calc Carb,

Ferrum Phos, Silica Terra 12x, Chenopodium Anth, Filix Mas, Granatum,

Kamala 3x,3c, Cina, Spigelia Anth, Teucrium Mar, Thymol 4x,

Cucurbita Pepo 2x,4x, Triticum 3x, Naphthaline 5c

Alcohol and Purified Water

WRM Clear  nat mur, nat phos, sulphur, arsenicum alb, nux vom, calc carb, ferrum phos, silica terra, chenopodium anth, filix mas, granatum, kamala, cina, spigelia anth, teucrium mar, thymol, cucurbita pepo, triticum, naphthaline,   liquid

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 61571-553 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength ARSENIC TRIOXIDE (ARSENIC TRIOXIDE) ARSENIC TRIOXIDE 8 [hp_X]  in 15 mL OYSTER SHELL CALCIUM CARBONATE, CRUDE (OYSTER SHELL CALCIUM CARBONATE, CRUDE) OYSTER SHELL CALCIUM CARBONATE, CRUDE 12 [hp_X]  in 15 mL CHENOPODIUM AMBROSIOIDES (CHENOPODIUM AMBROSIOIDES ) CHENOPODIUM AMBROSIOIDES 3 [hp_X]  in 15 mL ARTEMISIA CINA FLOWER (ARTEMISIA CINA FLOWER) ARTEMISIA CINA FLOWER 4 [hp_X]  in 15 mL PUMPKIN SEED (PUMPKIN SEED) PUMPKIN SEED 2 [hp_X]  in 15 mL FERRUM PHOSPHORICUM (FERRUM PHOSPHORICUM) FERRUM PHOSPHORICUM 12 [hp_X]  in 15 mL DRYOPTERIS FILIX-MAS ROOT (DRYOPTERIS FILIX-MAS ROOT) DRYOPTERIS FILIX-MAS ROOT 3 [hp_X]  in 15 mL PUNICA GRANATUM ROOT BARK (PUNICA GRANATUM ROOT BARK) PUNICA GRANATUM ROOT BARK 3 [hp_X]  in 15 mL KAMALA (KAMALA) KAMALA 3 [hp_X]  in 15 mL SODIUM CHLORIDE (SODIUM CATION) SODIUM CHLORIDE 6 [hp_X]  in 15 mL SODIUM PHOSPHATE, DIBASIC ANHYDROUS (SODIUM CATION) SODIUM PHOSPHATE, DIBASIC ANHYDROUS 6 [hp_X]  in 15 mL NAPHTHALENE (NAPHTHALENE) NAPHTHALENE 5 [hp_C]  in 15 mL STRYCHNOS NUX-VOMICA SEED (STRYCHNOS NUX-VOMICA SEED) STRYCHNOS NUX-VOMICA SEED 8 [hp_X]  in 15 mL SILICON DIOXIDE (SILICON DIOXIDE) SILICON DIOXIDE 12 [hp_X]  in 15 mL SPIGELIA (SPIGELIA) SPIGELIA 4 [hp_X]  in 15 mL SULFUR (SULFUR) SULFUR 6 [hp_X]  in 15 mL TEUCRIUM MARUM (TEUCRIUM MARUM) TEUCRIUM MARUM 4 [hp_X]  in 15 mL THYMOL (THYMOL ) THYMOL 4 [hp_X]  in 15 mL ELYMUS REPENS TOP (ELYMUS REPENS TOP) ELYMUS REPENS TOP 3 [hp_X]  in 15 mL

Inactive Ingredients Ingredient Name Strength ALCOHOL   WATER

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 61571-553-13 15 mL In 1 BOTTLE, DROPPER None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
unapproved homeopathic		09/20/1999

Labeler - HomeoPet, LLC (121272657)

Registrant - HomeoPet, LLC (121272657)

Establishment
Name	Address	ID/FEI	Operations
Washington Homeopathic Products, Inc.		084929389	manufacture

Revised: 10/2010HomeoPet, LLC

WinRho SDF

Generic Name: RHo (D) immune globulin (ROE D im MYOON GLOB yoo lin)

Brand Names: HyperRHO S/D Full Dose, HyperRHO S/D Mini Dose, MicRhoGAM Ultra-Filtered Plus, RhoGAM Ultra-Filtered Plus, Rhophylac, WinRho SDF

What is RHo (D) immune globulin?

RHo (D) immune globulin is a sterilized solution made from human blood. Rh is a substance that most people have in their blood (Rh positive) but some people don't (Rh negative). A person who is Rh negative can be exposed to Rh positive blood through a mismatched blood transfusion or during pregnancy when the baby has the opposite blood type. When this exposure happens, the Rh negative blood will respond by making antibodies that will try to destroy the Rh positive blood cells. This can cause medical problems such as anemia (loss of red blood cells), kidney failure, or shock.

RHo (D) immune globulin is used to prevent an immune response to Rh positive blood in people with an Rh negative blood type. RHo (D) immune globulin may also be used in the treatment of immune thrombocytopenic purpura (ITP).

RHo (D) immune globulin may also be used for purposes not listed in this medication guide.

What is the most important information I should know about RHo (D) immune globulin?

You should not receive this medication if you have ever had an allergic reaction to an immune globulin or if you have immune globulin A (IgA) deficiency with antibody to IgA. You should not receive RHo (D) immune globulin if you have hemolytic anemia (a lack of red blood cells).

Before you receive this medication, tell your doctor if you have heart disease or a history of coronary artery disease, high triglycerides, a bleeding disorder, or immune globulin A (IgA) deficiency.

If you are an Rh-negative woman and you become pregnant, you must tell your doctor if you have ever been exposed to Rh-positive blood in your lifetime. This includes exposure from a mismatched blood transfusion, or exposure during your first pregnancy. Your history of exposure and treatment will be extremely important to each and every one of your pregnancies.

Call your doctor at once if you have a serious side effect such as fever, chills, shaking, back pain, dark colored urine, rapid breathing, feeling short of breath, urinating less than usual, swelling, rapid weight gain, pale skin, easy bruising or bleeding, rapid heart rate, trouble concentrating, feeling light-headed. Do not receive a "live" vaccine for at least 3 months after treatment with RHo (D) immune globulin. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.

What should I discuss with my healthcare provider before I receive RHo (D) immune globulin?

You should not receive this medication if you have ever had an allergic reaction to an immune globulin or if you have immune globulin A (IgA) deficiency with antibody to IgA. You should not receive RHo (D) immune globulin if you have hemolytic anemia (a lack of red blood cells).

To make sure you can safely receive RHo (D) immune globulin, tell your doctor if you have any of these other conditions:

• 
  

  heart disease or a history of coronary artery disease (hardened arteries);

  
  


• 
  

  high triglycerides (a type of fat in the blood);

  
  


• 
  

  a bleeding disorder (such as hemophilia); or

  
  


• 
  

  immune globulin A (IgA) deficiency.

  
  

RHo (D) immune globulin is used during and after pregnancy. This medication is not known to be harmful to a baby during pregnancy or while breast-feeding.

If you are receiving this medication to treat a mismatched blood transfusion, tell your doctor if you are pregnant or if you ever plan to become pregnant.

If you are an Rh-negative woman and you become pregnant, you must tell your doctor if you have ever been exposed to Rh-positive blood in your lifetime. This includes exposure from a mismatched blood transfusion, or exposure during your first pregnancy. Your history of exposure and treatment will be extremely important to each and every one of your pregnancies.

RHo (D) immune globulin is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

How is RHo (D) immune globulin given?

RHo (D) immune globulin is injected into a muscle or a vein. You will receive this injection in a clinic or hospital setting.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely for at least 8 hours after you receive immune globulin. Your urine will also need to be tested every 2 to 4 hours.

For treatment during pregnancy, this medication is usually given at regular intervals during the last half of the pregnancy, and again after the baby is born.

For treatment of a mismatched blood transfusion, the medication is given when symptoms of an immune response appear (when the body starts making Rh antibodies).

To be sure this medicine is helping your condition, your blood will need to be tested often. Your liver and kidney function may also need to be tested. Visit your doctor regularly.

This medication can cause false results with certain lab tests for glucose (sugar) in the blood. Tell any doctor who treats you that you are using RHo (D) immune globulin.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your RHo (D) immune globulin injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while receiving RHo (D) immune globulin?

Do not receive a "live" vaccine for at least 3 months after treatment with RHo (D) immune globulin. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.

RHo (D) immune globulin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: rash or hives; feeling light-headed, chest tightness, difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  fever, chills, shaking, back pain, dark colored urine;

  
  


• 
  

  rapid breathing, feeling short of breath.

  
  


• 
  

  urinating less than usual or not at all, swelling, rapid weight gain; or

  
  


• 
  

  pale skin, easy bruising or bleeding, rapid heart rate, trouble concentrating, feeling light-headed.

  
  

Less serious side effects may include:

• 
  

  joint or muscle pain;

  
  


• 
  

  headache, dizziness;

  
  


• 
  

  feeling weak or tired;

  
  


• 
  

  mild itching or skin rash;

  
  


• 
  

  nausea, diarrhea, vomiting, stomach pain; or

  
  


• 
  

  pain or tenderness where the medicine was injected.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect RHo (D) immune globulin?

There may be other drugs that can interact with RHo (D) immune globulin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More WinRho SDF resources

• WinRho SDF Side Effects (in more detail)
• WinRho SDF Use in Pregnancy & Breastfeeding
• WinRho SDF Drug Interactions
• WinRho SDF Support Group
• 2 Reviews for WinRho SDF - Add your own review/rating

• WinRho SDF MedFacts Consumer Leaflet (Wolters Kluwer)


• WinRho SDF Advanced Consumer (Micromedex) - Includes Dosage Information


• Bayrho-D full dose


• HyperRHO S/D Full Dose Prescribing Information (FDA)


• MICRhoGAM MedFacts Consumer Leaflet (Wolters Kluwer)


• RhoGAM Ultra-Filtered PLUS Prescribing Information (FDA)


• Rhophylac Prescribing Information (FDA)


• Rhophylac MedFacts Consumer Leaflet (Wolters Kluwer)


• Rhophylac Consumer Overview

Compare WinRho SDF with other medications

• Idiopathic Thrombocytopenic Purpura
• Rh-Isoimmunization

Where can I get more information?

• Your doctor or pharmacist can provide more information about RHo (D) immune globulin.

See also: WinRho SDF side effects (in more detail)

Wilate

Generic Name: antihemophilic factor viii and von willebrand factor complex (Intravenous route)

an-tee-hee-moe-FIL-ik FAK-tor ATE HUE-man, Von WILL-a-brand FAK-tor KOM-plex (HUE-man)

Commonly used brand name(s)

In the U.S.

• Alphanate


• Humate-P


• Wilate

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Antihemophilic Agent

Uses For Wilate

Antihemophilic Factor VIII and von Willebrand Factor Complex injection is a combination product that is used to treat serious bleeding episodes in patients with a bleeding problem called von Willebrand disease (VWD). The bleeding episode may be related to an injury (trauma) or a surgical procedure. This medicine may also be used to stop bleeding in patients with hemophilia A.

Antihemophilic Factor VIII and von Willebrand Factor Complex are normally produced in the body. They help clot the blood when an injury occurs. Patients with von Willebrand disease or hemophilia A do not make enough of these substances to prevent bleeding, so this product is given to increase the levels of these substances in the blood.

This medicine is available only with your doctor's prescription. This medicine is to be administered only by or under the supervision of your doctor.

Before Using Wilate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Antihemophilic Factor VIII and von Willebrand Factor Complex injection in children 5 to 16 years of age.

Geriatric

Adequate and well-controlled studies have not been done on the relationship of age to the effects of Antihemophilic Factor VIII and von Willebrand Factor Complex injection in geriatric patients.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood clots or a history of medical problems caused by blood clots—Use with caution. These conditions may increase the risk of developing blood clots.

Proper Use of antihemophilic factor viii and von willebrand factor complex

This section provides information on the proper use of a number of products that contain antihemophilic factor viii and von willebrand factor complex. It may not be specific to Wilate. Please read with care.

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins.

Precautions While Using Wilate

It is very important that your doctor check you or your child closely while you are receiving this medicine to make sure it is working properly. Blood tests may be needed to check for unwanted effects.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you or your child have a cough; difficulty with swallowing; dizziness; a fast heartbeat; wheezing; shortness of breath; trouble with breathing; chest tightness; swelling in your face, hands, tongue, or throat; a fever; chills; a runny nose or sneezing; itching or hives; or lightheadedness or faintness after you get the injection.

This medicine may increase your chance of having blood clotting problems. Tell your doctor right away if you or your child have a sudden or severe headache, problems with vision or speech, chest pain, shortness of breath, or numbness or weakness while you are receiving this medicine.

This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made from human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during the making of these medicines. Although the risk is low, talk with your doctor if you have concerns.

Wilate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

• Difficulty with breathing or swallowing


• dizziness


• fast heartbeat


• fever


• hives or welts


• itching


• nausea


• reddening of the skin, especially around the ears


• shortness of breath


• skin rash


• swelling of the face, throat, or tongue


• unusual tiredness or weakness

Incidence not known

• Cough


• tightness in the chest


• vomiting


• wheezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Wilate side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Wilate resources

• Wilate Side Effects (in more detail)
• Wilate Use in Pregnancy & Breastfeeding
• Wilate Support Group
• 0 Reviews for Wilate - Add your own review/rating

• Wilate MedFacts Consumer Leaflet (Wolters Kluwer)


• Wilate Consumer Overview


• Alphanate Prescribing Information (FDA)


• Alphanate MedFacts Consumer Leaflet (Wolters Kluwer)


• Humate-P Prescribing Information (FDA)


• Humate-P MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Wilate with other medications

• von Willebrand's Disease

Westrim LA

Generic Name: phenylpropanolamine (fen ill proe pa NOLE a meen)

Brand Names: Acutrim 16 Hour, Acutrim II, Maximum Strength, Acutrim Late Day, Control, Dexatrim, Empro, Mega-Trim, Phenyldrine, Propagest, Propan, Rhindecon, Westrim, Westrim LA

What is Westrim LA (phenylpropanolamine)?

Phenylpropanolamine is a decongestant. It works by constricting (shrinking) blood vessels (veins and arteries) in your body. Constriction of blood vessels in your sinuses, nose, and chest allows drainage of those areas, which decreases congestion.

Phenylpropanolamine is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold. Phenylpropanolamine also causes a decrease in appetite and is used in some over-the-counter diet aids.

Phenylpropanolamine has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Westrim LA (phenylpropanolamine)?

Phenylpropanolamine has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Do not take phenylpropanolamine for longer than 7 days if your condition does not improve or if your symptoms are accompanied by a high fever.

Do not take more of this medication than is recommended on the package or by your doctor. Use caution when driving, operating machinery, or performing other hazardous activities. Phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Who should not take Westrim LA (phenylpropanolamine)?

Do not take phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• 
  

  high blood pressure;

  
  


• 
  

  any type of heart disease, hardening of the arteries, or irregular heartbeat;

  
  


• 
  

  thyroid problems;

  
  


• 
  

  diabetes;

  
  


• 
  

  glaucoma or increased pressure in your eye;

  
  


• 
  

  an enlarged prostate or difficulty urinating; or

  
  


• 
  

  liver or kidney disease.

  
  

You may not be able to take phenylpropanolamine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether phenylpropanolamine will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of phenylpropanolamine. Do not take this drug if you are breast-feeding a baby. If you are over 60 years of age, you may be more likely to experience side effects from phenylpropanolamine. You may require a lower dose of this medication. Using a short-acting formulation of phenylpropanolamine (not a long-acting or a controlled-release formulation) may be safer if you are over 60 years of age.

How should I take Westrim LA (phenylpropanolamine)?

Take phenylpropanolamine exactly as directed by your doctor, or follow the instructions that accompany the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Never take this medication in larger doses or more often than is recommended. Too much phenylpropanolamine could be very harmful.

If your symptoms are accompanied by a high fever, or if they do not improve in 7 days, see your doctor.

Store phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a phenylpropanolamine overdose include extreme tiredness, sweating, dizziness, a slow heart beat, and a coma.

What should I avoid while taking Westrim LA (phenylpropanolamine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Phenylpropanolamine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Never take this medication in larger doses or more often than is recommended. Too much phenylpropanolamine could be very harmful.

Westrim LA (phenylpropanolamine) side effects

If you experience any of the following serious side effects from this medication, stop taking phenylpropanolamine and seek emergency medical attention:

• 
  

  an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

  
  


• 
  

  seizures;

  
  


• 
  

  unusual behavior or hallucinations; or

  
  


• 
  

  an irregular or fast heartbeat.

  
  

Other, less serious side effects may be more likely to occur. Continue to take phenylpropanolamine and talk to your doctor if you experience

• 
  

  dizziness, lightheadedness, or drowsiness;

  
  


• 
  

  headache;

  
  


• 
  

  insomnia;

  
  


• 
  

  anxiety;

  
  


• 
  

  tremor (shaking) or restlessness;

  
  


• 
  

  nausea or vomiting; or

  
  


• 
  

  sweating.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Westrim LA (phenylpropanolamine)?

Do not take phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Phenylpropanolamine may also interact with the following medicines:

• 
  

  furazolidone (Furoxone);

  
  


• 
  

  guanethidine (Ismelin);

  
  


• 
  

  indomethacin (Indocin);

  
  


• 
  

  methyldopa (Aldomet);

  
  


• 
  

  bromocriptine (Parlodel);

  
  


• 
  

  caffeine in cola, tea, coffee, chocolate, and other products;

  
  


• 
  

  theophylline (Theo-Dur, Theochron, Theolair, others);

  
  


• tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan), and nortriptyline (Pamelor);


• other commonly used tricyclic antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), protriptyline (Vivactil), and trimipramine (Surmontil);


• phenothiazines such as chlorpromazine (Thorazine), thioridazine (Mellaril), and prochlorperazine (Compazine); and


• other commonly used phenothiazines, including fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), and trifluoperazine (Stelazine).

Drugs other than those listed here may also interact with phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More Westrim LA resources

• Westrim LA Side Effects (in more detail)
• Westrim LA Use in Pregnancy & Breastfeeding
• Westrim LA Drug Interactions
• Westrim LA Support Group
• 0 Reviews for Westrim LA - Add your own review/rating

• Propantheline Bromide Monograph (AHFS DI)

Compare Westrim LA with other medications

• Nasal Congestion
• Weight Loss

Where can I get more information?

• Your pharmacist has more information about phenylpropanolamine written for health professionals that you may read.

What does my medication look like?

Phenylpropanolamine is available over the counter under the brand name Propagest, and with a prescription under the brand name Rhindecon. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• 
  

  Propagest 25 mg--oval, white, scored tablets

  
  


• 
  

  Rhindecon 75 mg--timed-release capsules

  
  

See also: Westrim LA side effects (in more detail)

Wal-finate

Generic Name: chlorpheniramine (KLOR fen IR a meen)

Brand Names: AHist, Aller-Chlor, Allergy Relief, C.P.M., Chlo-Amine, Chlor-Mal, Chlor-Trimeton, Chlor-Trimeton Allergy SR, Chlorphen, ChlorTan, Ed Chlor-Tan, Ed ChlorPed, PediaTan, TanaHist-PD, Triaminic Allergy, Wal-finate

What is Wal-finate (chlorpheniramine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Chlorpheniramine is used to treat sneezing, itching, watery eyes, and runny nose caused by allergies or the common cold.

Chlorpheniramine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Wal-finate (chlorpheniramine)?

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not take chlorpheniramine if you are allergic to it.

Ask a doctor or pharmacist before taking chlorpheniramine if you have glaucoma, a stomach ulcer, severe constipation, kidney disease, urination problems, an enlarged prostate, or a thyroid disorder.

Ask a doctor or pharmacist before using any other cold, cough, or allergy medicine. Chlorpheniramine is contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine.

Chlorpheniramine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine.

What should I discuss with my healthcare provider before taking Wal-finate (chlorpheniramine)?

Do not take this medication if you are allergic to chlorpheniramine. Do not use chlorpheniramine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

• 
  

  glaucoma;

  
  


• 
  

  a stomach ulcer;

  
  


• 
  

  severe constipation;

  
  


• 
  

  kidney disease;

  
  


• 
  

  urination problems or an enlarged prostate; or

  
  


• 
  

  a thyroid disorder.

  
  

FDA pregnancy category B. Chlorpheniramine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

How should I take Wal-finate (chlorpheniramine)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold or allergy medicine is usually taken only for a short time until your symptoms clear up.

Take this medication with a full glass of water. Take chlorpheniramine with food or milk if it upsets your stomach. Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

This medication can cause unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cold or allergy medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking Wal-finate (chlorpheniramine)?

Ask a doctor or pharmacist before using any other cold, cough, or allergy medicine. Chlorpheniramine is contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Chlorpheniramine can decrease perspiration and you may be more prone to heat stroke.

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine.

Wal-finate (chlorpheniramine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop taking chlorpheniramine and call your doctor at once if you have a serious side effect such as:

• 
  

  urinating less than usual or not at all;

  
  


• 
  

  confusion, extreme drowsiness;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, nervousness; or

  
  


• 
  

  weak or shallow breathing.

  
  

Less serious side effects may include:

• 
  

  mild dizziness, drowsiness;

  
  


• 
  

  blurred vision;

  
  


• 
  

  dry mouth;

  
  


• 
  

  nausea, stomach pain, constipation;

  
  


• 
  

  problems with memory or concentration; or

  
  


• 
  

  feeling restless or excited (especially in children).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Wal-finate (chlorpheniramine)?

Other cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by chlorpheniramine. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all other medicines you use, especially:

• 
  

  glycopyrrolate (Robinul);

  
  


• 
  

  mepenzolate (Cantil);

  
  


• 
  

  probenecid (Benemid, Probalan);

  
  


• 
  

  rifampin (Rifadin, Rifater, Rifamate, Rimactane);

  
  


• 
  

  zidovudine (Retrovir, AZT);

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  atropine (Atreza, Sal-Tropine), belladonna (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

  
  


• 
  

  bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

  
  


• 
  

  bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);

  
  


• 
  

  irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro-Banthine); or

  
  


• 
  

  salicylates such as aspirin, Backache Relief Extra Strength, Novasal, Nuprin Backache Caplet, Doan's Pills Extra Strength, Pepto-Bismol, Tricosal, and others;

  
  

This list is not complete and other drugs may interact with chlorpheniramine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Wal-finate resources

• Wal-finate Side Effects (in more detail)
• Wal-finate Use in Pregnancy & Breastfeeding
• Wal-finate Drug Interactions
• Wal-finate Support Group
• 1 Review for Wal-finate - Add your own review/rating

• Ahist MedFacts Consumer Leaflet (Wolters Kluwer)


• Aller-Chlor Syrup MedFacts Consumer Leaflet (Wolters Kluwer)


• Chlorpheniramine Maleate/Tannate, Dexchlorpheniramine Maleate Monograph (AHFS DI)


• Ed ChlorPed Suspension Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Pediox-S Suspension MedFacts Consumer Leaflet (Wolters Kluwer)


• QDALL AR Sustained-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Wal-finate with other medications

• Allergic Reactions
• Cold Symptoms
• Hay Fever
• Urticaria

Where can I get more information?

• Your pharmacist can provide more information about chlorpheniramine.

See also: Wal-finate side effects (in more detail)

Wytensin

Generic Name: guanabenz (Oral route)

GWAHN-a-benz

Commonly used brand name(s)

In the U.S.

• Wytensin

Available Dosage Forms:

• Tablet

Therapeutic Class: Antihypertensive

Pharmacologic Class: Alpha-2 Adrenergic Agonist

Uses For Wytensin

Guanabenz belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).

High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Guanabenz works by controlling nerve impulses along certain nerve pathways. As a result, it relaxes blood vessels so that blood passes through them more easily. This helps to lower blood pressure.

Guanabenz is available only with your doctor's prescription.

Before Using Wytensin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of guanabenz in children with use in other age groups.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of guanabenz in the elderly with use in other age groups. However, dizziness, faintness, or drowsiness may be more likely to occur in the elderly, who are usually more sensitive to the effects of guanabenz.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Yohimbine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Heart or blood vessel disease—Lowering blood pressure may make some conditions worse

• Kidney disease or


• Liver disease—Effects of guanabenz may be increased because of slower removal of guanabenz from the body

Proper Use of Wytensin

In addition to the use of the medicine your doctor has prescribed, treatment for your high blood pressure may include weight control and care in the types of foods you eat, especially foods high in sodium. Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life . If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

To help you remember to take your medicine, try to get into the habit of taking it at the same time each day.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):
  
  • For high blood pressure:
    
    • Adults—At first, 4 milligrams (mg) two times a day. Then, your doctor may gradually increase your dose.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss two or more doses in a row, check with your doctor. If your body suddenly goes without this medicine, some unpleasant effects may occur. If you have any questions about this, check with your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Wytensin

It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly.

Check with your doctor before you stop taking guanabenz. Your doctor may want you to reduce gradually the amount you are taking before stopping completely.

Before having any kind of surgery (including dental surgery) or emergency treatment, tell the medical doctor or dentist in charge that you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This especially includes over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood pressure.

Guanabenz will add to the effects of alcohol and other CNS depressants (medicines that slow down the nervous system, possibly causing drowsiness). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using this medicine.

Guanabenz may cause some people to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Guanabenz may cause dryness of the mouth, nose, and throat. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Wytensin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Signs and symptoms of overdose

• Dizziness (severe)


• irritability


• nervousness


• pinpoint pupils


• slow heartbeat


• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Dizziness


• drowsiness


• dryness of mouth


• weakness

Less common or rare

• Decreased sexual ability


• headache


• nausea

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Anxiety or tenseness


• chest pain


• fast or irregular heartbeat


• headache


• increased salivation


• increase in sweating


• nausea or vomiting


• nervousness or restlessness


• shaking or trembling of hands or fingers


• stomach cramps


• trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Wytensin side effects (in more detail)

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More Wytensin resources

• Wytensin Side Effects (in more detail)
• Wytensin Use in Pregnancy & Breastfeeding
• Drug Images
• Wytensin Drug Interactions
• Wytensin Support Group
• 0 Reviews for Wytensin - Add your own review/rating

• Wytensin Concise Consumer Information (Cerner Multum)


• Guanabenz MedFacts Consumer Leaflet (Wolters Kluwer)


• Guanabenz Prescribing Information (FDA)

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